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Radio as 5p. Comn paso pses-o iar - La Junta del loe, pr In tan- ienbrs del P. R y d Is sabar 2 las generates en Usamsdo s decidir. F esoparnt en orpere, esni-i a m e sn te y president del omi pro-G a eo r e a ria l is. Sda- Oar c n es p i Aleo e n iptal de. Ri oxima-" E ounic. In e, de n a lapb ezda n habic- ife F-.

Sateno utotica. C iitoc o ra i ebt tlon a presssnta" as-mt de las-echn delo hs nehao videna dci lsrlidoadocs uamhes d oe s ie o dere sen te A ro sn- a eer-er. Qid itranS. Ias1ui nitecuv huiwa er dcl patc prciensua abedo-it os Elotos-ilcst's gran.

Alberto Menocal. I 'Naturaleza Macrio". Julio Girona. I fRodulfo Tardo. Carlos Enriqurz, Agustin Fernandez. Par Escultura: Franctsco Ant-ua. Enzo Gallo. Tallas 36 al cortos y regulates: Modelo con 2 botones en color brown en la Traje de casimir en gris y beige con ravas en color contrastante.

Modelo de dos botones con solapa estrecha y aberrura en [a espalda. Tallas 36 al Epalda abterta. Tallas 35 al SI des.. Arteagaz Hay iabado, a las do I tardo. La fluminnaci6n del arbol -total menie a cargo de la Generl Elec, tric -comprende 1, bolas plia tica de distintos colores. Se requirieron 30, pies de alambre para reai- Acaba de ser designado PreSidenzar la dedoracidn.

Com una fina cortesia 1a Corn- UNESCO, con la cual mantiene contacto permanente a travds de la pafiia Cubana de Electricidad pro- Asociaci6n Internacional de Asociaporcionara absolutamente gratis to- ciones Culturals, Cientificas y Fido el fluido que consuma el air- los6ficats, con sede en S9lerno, Itaol. Raful Vallejos, acaba de comunicar El centenario del nacimiento del que se entregara al distinguida in.

Culura Americana. Qoieaps 97ljor 64 cAluaobra. OI ' I oj or. L rico igo se rr. W-3e00rd M i es. A- s brevrene, a Cate Joven in. Q do tu oyeron aguna vez. L telectual que ttn dignamente re- Me an que Un pign del None wel6n A mi1isi Cr titt40,' 45e pret m iurada fluenti gut teni Redfacibac.

A- Abogado d Ia Universidad Ca. Aunc ao E La p al- rt gut ca ue d otr veco y yea aabe que I rapstl cci todo Pre do Bllcri b got, hi o eu tess sce gredo--ndo mere elbraocada de aol o tru- te agrdezco mucho.

Mi pruner Ya ea version st ha perdido y Mae oiaomrnes achualmenlte en pren- a. El ts-abeonsabre Erosk. Esl alizado en e Carts hata hay. El nifi ar o h t i a o pea ois eu n usptiadidt. No es feliz en este Paraibao genericat que presidan a las nvez- Ultima etapa de su video. Piens en La nieve bonita. Era en un co mprr sa de Cuba.

Horaei Ferrer y Ser-fin yendolo del osvidi cuantoe rel. Du ra os ha a e o ubI oroerseoaitee i Espinosa. Aludo a eos inconformes tabo pare ion pocus alumoos si Cora tibetadores cuye versnoi primers pigroa de nuestra edrci6n de ayer publcamos la clabonando activamcntl on Ia vestido 0i m6s zOpOtos que los que 1e-s que rechazat toda solicitud dc at gunsa es p oab Lad y d ene debian iser reocugda teficamagnifica Expoe6n del D e sumdetoexamen de concieici par no dsiotincidn.

C e I s lirmemene gue Ia aprobaci6n de un estupendo folleto ilustralivo sc do e Das-io sa oes Ia oraci6n infontil-, y odem6s a leer, suerte vierte sabre elio par ata- S lcudame a Ins tyn. Pronto corri6 Ia voz par at mercado, ar pedeotat Ciento si Ia gents tsbrtadona, se nos es- de negar tu concurso a un propolegislalores no debe ser objeto de apasionado ibal e sino de estudo libros editados en su Imprenta toda Ia ciudad de gue habia "F ado el inspector ge- que aqnise sufre en el Camio.

No se orals con ta] icicativa de favorecer a para divulgar las producciones Ii- net-l do "intusismo", aoejercici legal de una profe- P que caminos se tonan?

Los decidirse a pubLicar Lo versiones Con In apuntado, creo haber csle o aque] sector, de buscar par cameuos retorcidos y lortuosos Ia trarias de sus hombres notables: corts. Es decir, los pr que de vivo voz dejabsn ir n ofrecido, unque muy somersSi o rn, y particular, del gremia doe modistos y modrotas, Losqes oa a crlgbd s aittrodad sir sos hogares.

Ha- menir, Ian pautas gcnirleasa eu preeminencia de urns profesionales sabre los otsto,. Via, pregunt6, y con cora de pocos ami- vieti. No aquellos todavia v1s-b pautas deinitivas quo, reglamenando Justamente un tmportant- ra titulado Tlierrilde-1romisa , gas, sentenci6: "'Esto no puede tolerorse!. Sea-n deIs Htstorta hictera io pethmente nia algae inas ii ae estlnana util: Ea coecoivisiad. Penetrado deIne di- acoimpa ar, en aigona ocas1n, a ndeeo adnurao. Y aunque ten'an unos monos de deI la iteratura hispanoamer!

Atdo en Scos a] que hay que soineter Ia cuestidt, dpreciamos, comcidiendo con do-pu- nutsitn pals gue, pesea su quiet- cosa que buscoban, y enseiiobon a marovilla a ancho y alenoa" y Ia de Alejo Car- indas. El inspector habia verificado noda menos que aun valdria citar otras: "Daioa ncIarse Com labor de ctedra a pe nmibra muchos pasajes doa tatdva eacahsadcre Barbara".

Como cubano una actitud seclaria, puesto qui eniraia, A contrapelo de las rea- con una lmprrnla Naconal donde ochenta inspecciones. Y en todas ellas Ia misma cot6s- -La voragsne", de Jose Eustauo not. Mt idea era instruir ptev-e- he aentido el dolor de ver excrito. Ion nifton quo antes andobon desnuditon de- R era, "Dos Segundo Sombre, mente a tos mejores -no s6o par hajo el nombre de Francisco Vipr otra porte.

Par ser sertores anr atestro p riudico, en cuya -. Denuncioba ese "tremendo abuso" en nombre dadurca del Cd. No a, -ddrdbin m ararscIdas vens- 'sert- Is gloriao pNraunqlueai aeLonea H-deshoria n u ua qpinroducir a Ia Ielacios proycciad las Ignora totalmente--porque no a quienes envi6'el larmante informe.

F nrear c lnvantar el espiritu nacrmiles do nifios decazose, desnudos, hambrien- qu ahora toos, por consecuen- tste erma sndsque por sun nobren nesnter s. I dr sit ftrs Mats- do eeoc monjitac os un doechco soncial a todJ see Comrra lelicidadIngradapnS sect.

L-con VC. E que no conocemos. Por RamiroGuerra escrdals 'srs nustroon 'sr,o no- recho do las padres de los niios a disponer do su odu- c61o con su dolor en un lugar desu. Hosts coma egoista es deJ cotrrente mes. Auads y nueva sen- prsa en Ia Imprenta Nactoal do agradebte.

Bogota, en Contene lo gal- -pelgroso ya que no hay enemigos uail -Ea en Ona biblioteca arit- --concurredisims nempre-- de-, La iar, no priven sobre. Tal conven- ntin e los lbros colombianos que ise otro gran artifice del verso, nismos, anglintsmos, neolgismos. IA cnimtttd trabaja groal en s deapt par hebe L idn Biblotmca de I Socieisi Enonrcmi-ntito- obrc [a burnc iniencron quo ansot.

Fn- Apuntaciones Idiomdtleaa y Corre- grantes sde los primros doce Ace- demis, al coma inditcaciones so- Los irboles tienen hojas todo el con s reeconocida competencia a manifestando que empeios tan cuemas Pris aba.

La que se cae deja otra on los entusisticos alumnos funda- generous como' el de ia fundsaestsn Ilamados a deempetiat ei Is orbentin be le tit-esoa cc- Rest-epo.

Por oh Is name, Et cselo ttemprierau. Sc Ia nbr-a a. Cat on ceaparron. Antuehunente is Direcntar Seeaforinacisn p eonslanto rovach -annre dcl 9pagti. Pet-n, tanza pribctice Se Ic tocuela Cu- ioteccate pare nit-os sic 4 a 52 El hoambre qac renauneio a awn Genca encarnac eirtpo Sr rntrlrctuci go- Felix Restrepsi.

J, Iit61sgo, p nile segulr, de one manora ni- spet Sc gui La, punstmatsdad banal e StBlbiontccato, 6i h4 afoa. Jce Manuel Rises Seecocol. Mi- di Ia evohutitn del idiomros osl- bee ilerea puntuisnlo e h le. Llegaria c so a so nargo. It-sra tr, sic p t-nv ic rlc do tib ess it en -u clc pu b li-a n fi m ro es ra glo y Is digoidad per-sonal es- Dese 1. League de. El 0 de Fo- -No so,o aes pet-Sdda aolan p entuasma deie ci pri- eote note inlorinclive, debo noran las ft-tiles e ioacceulils tic- a Is farna Dc Ia tres-ra art-ant-an Guano.

Caroacha trsbejs en brero sic hlsi convalenienh hide- -,erdiuda' iD6nde? Otisc ho 35 at-os vseoc at pueblo en tna IaAbo. I i s emn aisn "p. Coma camrmman - Con o habttualexptrlencia Sca laos paro n gerlt Cc.. El tabac le devuelle crca de cinco horms de conversa- Peleando hombro con hombro al Pricticamente ejerciendo el man- -elt par gue an? Titi do Bronee. Desde lot ocho afis. Dedo mn -n. Camndante ya. Dgrldo el cci- agune miamnta,?. U famiia y combate de Soroa, herides ten i0 Zaias e1 hosbro qus ba mY a w aeua en tate nsos ]t-hneta no: n qle b iscucic i Estedos Unidot, sino a lot p1eplndo us diStl hondonada de un- cia.

El 13 de enero de 18W en Re- todos log grandet afectoe. Pert teniente-coronel Gallo: herido tam- leccitn d e vids: una vida en hey qua Pedir PI. Padres ehilos, La amistad. El co y a auudad-y- a-b. LaA dad- -"'Un art de ivir" - E arte de pensar. Bulandas de organza de nylon blanco o do "tonos muy pdlodot con lotaz de oda ehilos dorados y plateados. Tienen zipper y estn lorrados inteormente en raydn. A'" Biciclta "Garton" de fuerto metal esmaltado en rojo y blanco con parrilla. Para nios de 2 a 6 haos.

Las con novedoso cabo doe lUcite y lorrddasen tafeltn negro. Sotobrero mjican d nae. Crepd y Tafet6n estampodo En todos Ins londos osculos nois en boga - en docenas do nuevos y atraoti' vos discos. Genrelos alecanes de toa marc "Genos'. Ligora, plegable y elegante Mesa auil,ar de qran uhicdad. P - Juveniles Corbatas de sda natural. Del 12 al Tambien en corduroy estampado o en gabardina beige.

Tallas desurtidas del 10 al Valian 5. Del 9 Al Jen-b a ka. Pero de todas maneras Pero,'entre lao, clanes pobres Ins Campos de Cuba". Los dos disfrutan de fama. I isque aimularon nor enHo usted puede. Primer oshmero, 15 son atnicos, mm palabra. Lons que quieran saborear rica potaies En New York, banquete al deben de tener en cuenta Cgook6 y 3. Remocion de los altos mandos Los vuelos 1Termiiha. PR JCsT. AL L brigadier giners,.

OCA C R.. El mintAro Idosu acoerdo mutual di viola y In 6ir-constniocliy an tia ci. Osa rb Arana, h bta ol o. En Isaana de ayer rccb 6 a Franlaco Zerdd.

Elt Sora. I Prontirpo pars hay ibado', i ex cuartelmaeotre general si enecear lgislar "Parafron- cargo la operacl6n y el rviclo t-1pinteria, critales nuevos, lontala-. Jefe de la Eaetd M norteamericanos empleadon pot or- tados por es. V re ordo F o di poan dettadas parked a h a reu Cielos parte nubledoa 3f nutal. El rorel quillermo Ramn ONU curammonstas, organmzaciones civicas.

Prezi6n atmosfiri. Al ex embajador en Costa Rica, cionen Undas, en Egipto. Viento "n dd raspre-edetrariporte de da Fuerza A6-T bhe d a o 4 - i a 1 m baller. Total di l I. Nuevna Pa : II Olicina. El dirmo aregs aicont enido mi tab. El estuche considerado.. Ene elmismo lto Seembarcaro rtm a difeconte cu1sn conlorme al ordenamiento que al e ev San Lorenzo Ente organismo ci emdlciembre 14, i'nitenjor-dena a ]n exreana pagor t[odos ] dadet do Estados Unidos, via- Mia- -efecto se har de cada expediente itierde sohe l mitad' orentat Nnr.

Nkib mi, Ions siguientes pasajeros nubanos:lconforme alas disposicmones del re-. Las importacuones de viveres rea- te de Ins Estados Unido y parte del res do Azuiar nnmbcd ,yer presi-gapelo al triounal para que le res- Eduardo Le Riverend v Bruzone.

Merce- , noviembre por todes Ios. Oscar Echo-El otrMne i -rioc. Menorat pot il'gman parcti del Ocesn. La juntaa DencarrIt6o notrens abtrranneo mnim Maitinez. Las bajas presiones presentan un eguldamente eligid a s sucesor, cas, aunoue provocd el descarrila- Ventura.

La cararcioYank, it director del Noticiro Na- Expres6 el doctor de lo Torrecarne fresca" , ouintales deTennensee. Scomeno en a eeera mecn l , Manuel Alonso, Paratende Parlamento de Aemania Occ ddn- o y " a" qlooos acosuntos relarmonados con Is indus- ue haste dicha fecha lan recauda- cebollas; 4. La aprooa- cIn m is Csyo Guano del Eote. San debate. El ttan oa fue inn c-ad pocsrveteeo. Ini es Murray, Mario und z Mesa El tran-na Ram.

Pa esri l-oe ds-ta elm' rnolttsrdsa a o y68, d e do Taua. Sera- eje Desmente Hardling s renuncia i-n tiempo despues. Roertoio anterior se descomponepari m-ii quintales de aa l r 1inta do pnco en estabilidad desde ayer.

Walter R euther, e minguez. Harding re-leIsn Organuzacio. Sindoical Fu- Caizadilla, Silvia Teltechea. IoCantayo delde Citnd cres6 de Gran Bretafia. E rector do e o La constitu1Dbrers del Automdvil, declare que gao a. I Impuesto del Tim- IHtor.

En viaie "directo a bordo de jin Susan W. Mercdes o r 58,ducn 0, 1:iderto que regula lan saccti Elizabeth Paez. Pern a proar Pez. Ignascio Esteban y oJimn. Josephd ole LampariUa ; Miguel Lebredo sa Salomon Terrner.

Iveitepasqomen el fiscal intaend dos Cohn: Bafael Costa Larrado. Edici6n del viernes, 14 mern ole niion sninitos. Edena Mate.. Cindyitos de robs y encubrimiento a l! Camejo Acosta, n'I-irezSigans. Barr" waharlal Nehru, dorante la visita.

Tie duties an asevlurlr qua habri sa CIO 61' curso monogriflco tie Literature tie ca, qui6n tin gderrik disfrutar puedea air agrididas par al ex-', a t irtnlo nurstrot confliclos 1. Puts an cuniquier C. LA L6. I I dijtas cam. Se araUlri qua agun pasads I I I 11 A tie ongen. In Poesla, Incluao, as un "recuer- relacl6n do personals afterlda. La His- do sonoro"? La funeldn wt? XrAfICa enLque so a,.

I curriculums, tie Pedagogis, La le otru vertex die Europe, mmo cartelemp an d do ones tie Ia oculIaditiramep, las bandermis b1f a Ir 14 ,ujorAci6n, a capalclas do toda palriolisma, do prop6siln Como aquatics conocl!

Clar tog sonstioustatorlos an atomism,. Su pro. I y on lots pedegogos. Mattson; Im linda, con 1. Atracti o: a Ia, omisnin de una litatestA inequivata y enters. Cornionza-a deiva- m-6vU ,Como otro nnanummombs llt.

I lam siffulentes materials: Ampilad6n, ,unam cumentos d6- necirsenow, aqu" Investors do vices. Laires convertfilom, ficil, regalons, qua tred. Camal del hotel,, terrible elisculencia. I I 0 logi Jilin. V aloracion es: M 's sobre I Id6itticarnente un grupo tie I dloo index cis Ia antigua opulencia, ate.

Cuitando hill nit,. In doinle Ofinaldoor, ca. Antefio, eleiUvAnstrate, Vietus era las ontriess trilgicas tie too bombar- habla tie appears. Do c6ndo an cuitaft Doom Ida. Istema qua nos Universidid. Desplids, an all Mo. P do IA volveria. Lant chiledras de lax unlvor convendriA. Goethe, par aim,. Y, por of ,,,,,,,. Al fin, Vkow ma of" on Inamemon-olonew; p-c a dspukx de habernne viola I do sum contenido.. La dirt parquet list tales Ins dos faxes da tortes legatee a quo n de oil juventud, y, al vle o parsece -Irs, porque ,sea Alvarez Can't.

Fonsecil y y. Me me. Todo esto, deade lueNo. No ont Oropongo am. Pero adver JI qua no me inter. Ull I dI -r- prafexor do nogunda einnfl conocimientm queen ,an uplacto Ill, I brim, un Versailles mix pliquafto j te, qu.

Los graduados' tie Filosofis. Incomplete tie qu. Durrositte ate via. Ia del Rey SOL hernias teniclo in me. AgroJJ6 este protesor ban obtenido sun Altulos Para so. Parece qua it. It con. La Ironton 11tanlas cit. Moulin Rouge, qua is tolaribiL. Me dice: Va.

Para me gradilan de doctors. Apar' En to formal -ill ley- now fundamentalss' duranto lon cdatro iragos its Europa parts no hasc- rin to uue quienn; pem toldo, Us. Cuarido no an edo'es patitica, Se'tnta de un I ,or, extirosa all tolu.

I l9rij ,,,, dolvnt. Ini -a. Doctor" do par al Deparnmento. Ell In' an Ira arrabalas tie Ia chided nos aventum Afortu nadamentr, nu union cumaboo soldisdos kanoiricamos via sin. W uno sinocuado prueba list dlb- mmuphaut' 'Joe ii virtue do esa obwervaCl6n mucho qua trair y no Ia intent. NO he via- allogadow; tie reciente gra- eviler un motive min pare al cre.

Se ton. Oigo a. I liar ianuciournente lam pan I'll I.. IA ,gv,4 ,,,,.. Calle, preguntar: derecho, a liss sehores. ZO as qua soldado russ. Naturalmenti, 6ste as In pre-guem, donde in no que- T.

Par In calles gollitertIm to, an 1. No itudo, par oupuesta, a no cumbrir Ism citedrat. Es forma men. Us, aunque India mean lam mks al. Fonseca, an qua al aspirant a oil. Hermeticarren- ratoo pan al "Parcloolento domin.

I pcriencia y con su ca. I IncoiUmenot. I :, :,. Mrstwill; lam. Coca qua an lot doinfis content Wo dejando mi wanderhast an lit. N L61 esti court y' RUbl. Patrons, de Cub u-"' So: d. Una rina p-iosa. Thelma de la precio de uno mu 0. B, T. Lin Proyeetor de Numerwas lu felicitaclones. I Carldad G6;ml repose del sefto P. Is biili-im. Ca- Flor Mprilarit. Adriana, Martinez. Adriana Bachiller.

Caridad Arteaga de Betancourt y dome. Ito retraimiento. Los sefloret de Dihigo se encuen. Adriaps tan en los Estaclos Unid. Cachita Bofill, encantadora esposa dez, errer de Bel4neourt. Adriana Mo. Otra respectable diumia: C2ridad Es.

Lma V-,-Il.. Siguen IDS maludon; para Bob to. C" al. FA In espom del excellent J. Maria Montoro, tin gentle. Una bondadon danna: Carded Avi- Carues G6me7. Articulos de actualidad, I Cariclad Sales de Marlm6n. Marla Carldad Al. Zoraida Alvarez, Interes-le "po- ventajosos precious. Idamente Is xiAmpre int:remn-Ijoven y bella came. Henriques, berinum muy querlda del H Lists ara comer Coo 1. H-1q-, rays nbrit Carldad Puyanz de Dellund6. Ins disfinilonsa.

Completando esta p. Otra Joven dams. Las seflaritas: jpor Europa I Spurt. La schorita Benitez, cuys labor por Adelita Fonseca de M. Otro Saluda, de los primers, par. Un saludo cordial pan Carldad Pot In altruista y bondadosa metiorita Ca. Ramirez y Romero. Cariclad Delgado y Feble. Mqd ,ll. M, d, ffA. Piso No. Iloy: Nuestra W ore do 6 li Mi9rcoles 9, Duke Nombre It. L8,malso l0bropla SU, La mob. PaRvelos do Soda purat Tella. Calls 12 A 17 V I A, Videals. I "tics I..

I V P'l,Coined. I- oas ,. Authn tic. Pvo on Ir" I I I cjc -" ,ual I era ,I '. I I Aid se inf. VLAindea, Las W. Qude, cladii 1. I IA Son Ma. Abn do ]a C. Nfn oc no h n e porid otr,,,, I. I-,oci n I. It ,,, ert, d,1,,necl,, If ho que'era on "escla- de 'I, I I m agii doctor. I I I d1jo no era tin part Ulprecilliq flattlitic nrotig.

I , 1, sefiores sonsdar r," ,go R y Ycj; lox cbma retolzmdu durasite Iu adqua cam. Yn -, much. Cummilic, rererldm comiskong tie. No habia am- i, ,quje 1,. Axial me -, Joint. Fodo: Vittax. Gran Y no talman an matisfaccidan loar diloo pr,6xlmw, m ajwtw Sl -,art Ilegainan a I,.. X del. I on ; ode ,el Pimento P7m,i.

I ,i o do I liy-' Pod,, 1. FEU, p. Ila- d. I i a 'dgs Un oct. Agvc, 1. Ultum 1. I : roldn"Ito do "'P. Vic niberto at los-carnetsde idenl34ad que ban clectora. ChibliP y an respaldin a Is. Intimidation: calm as 1. Tambien lograron omi lot repov- Ia palabra tie orden, 0 tie desor-, "I preselitaintes. La Habana par carrete rdn tie b moid9upremo. Ica Ir e- 1. I er I CoVente. I Co ndI6 P. L Alvar-, o'. EnIva idap bra on I fiflai! Pis los veinte ahos do edpd, an qua,.

I progride Is an Santa Clara. L bra do los vinculam'disciplinartom. I principio do autcrided. Porque oil ayer el mi del Paril dato a In presidencla, dnct. Suprewo Acclon Uni "a. Juan A, Echeivill tiorl: a. I concejal E.

Cim e In do La Habafis Marianna. Guaria- I I Vidal kl. I ,or o-ti I ciera an varlooXerloicilcoo cle ent. S Include, itcreim, I ,ritifinclifra a Emocionado tribute en " m, , numt. Otras noticias de la ContraL. Direc Cc j r I pria. Ia hadianern, doctor Juan Francisco tin tie, 1 thovarria, pars npowent.

I' ditiloidis all in L ,,, 1,i, nic Uden 1. Sala ill proaddente de In Comilitin tie Fonder. El doctor Houncro"Valak dtoxlia- vas,. Ida Gabler 1. Barzo ,. Lox tiny nes. Jorge -I. Idencial 'Agramonte- 1, rr sea elde orldtar hiud. Justicla, qua fluuti me train patizallores. Cohan clocto as, W 1. Min con lit Via Blanco y porn ratify.

El doctor Honiara Val -a an dades Y donn ,a 60,. Hariall,' on viola truildraci6n, guladn par on rnuelta con Idato p -Ia tales etnpleadox 4duro. Marks' a no dor curso ill proved -lit. Old Cuban. It inver cime cmatur. I Chat. IS Jurlm ill ]a. Pur Dion th innego. Pero que me doembria Ins. Univic del oonle. CuUmen y San Be,- expoaaminvoi.

D all. It Sep. Remain In fins door: "Ya an digit Sell. Mninwitud" el--pak rb econdinim. Rona- ";MuY olimewous I. IS dcoulL. Ill SI fiernme, ammmumd. Is' 1. Cf,,I,6 S, Coma plarde en gravis. Y In exte l',a, de an aganin Y squitirn I'mrso do? Llso, Rite M, relom. In ,Ccta 't f ra optimism. Sol oil' dji, d, S" U. Par ,t4 a. Parrome,, I. USES Cristo 1. I] ca ni pdull I I ,N, ,,,. Cflor, Ailing -in, y he inum"j, In. In PON inj Cut ,. Unt I ennorm A ]a Jousts, 'H. Y qua ine. If fencla d, ,.

I onic. IN an, g-i Industrial. I Manuel 0 1-radoo. Ncr i'll crion"'I". I to Double ". I vmdSd- In- cimall pastor, Nos Mocce. Ma y lco, Is h. IN, ,,,ims"m In"'ll Pop L. C piumormc union I d,,, b,,Ilc. N ,tdc. III Ulliel-in, 'n 1. Ing ,burn bit. Ubmm ,,fee. Zoluithl an a' thadval 1.

D Pill. Iculloom dial,"i Piro oil. Pasuble, -in- m-bo'blon puart. U ;ic"'tic c, pan ivo que No cielo 'de Cienclos E. Detu Floem, Not. So arpoll to i"tual" Y lofi llllml 1 1mo do ausicuto, tut-tin, inere 'cruch an, tiuvrlon.

III, ii stim wilW. Allen, vict I. III- tn, "n"a to- a,. N blioullas dl to. Ili experie do lepubipterits.

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Spedim, ha tormilmadn Im tax UILded. Poe Unit ,I succon'to Logs that, la,, rather are career. Soccion Unic. Igo caust. There is no complexity in his world, no ambiguity or vagueness - there are only his own ideas and mood, embodied in music. Red Book was specially created for private listening - two in the room is too much to understand him. I think it's played on analogue synthesizers, and it's not the tapestry sounds of Hypnos but more the stripped down version of ambient house music.

Things move a little bit, there is arpeggio's on the piano, and even a bit of percussion. However the highlight of the cd is the fourth track, which started out with a voice going through a vocoder, later on forming a duet of voices and brings it close to space age popmusic.

That is absolutely a great piece. Even with such a title for the cd things can't go wrong. The new material is completely acoustic without usage of any musical instruments.

Only field recordings and feedback. Everything melts down into electroacoustic drone ambient of live tension. The music consist out of military drummings, darkambient battlefield sounds, with vocals telling true happened stories and poems taken from the 2nd world war. Monotonous factory loops slowly pulsate and generate sickly pictures of mechanical schizophrenia.

Ariu Lab deals with documentary, video installations and visual design. Ariu Kara records sound for all visual parts of the project. Ariu Kara plays gloomy music of post-human future, dead earth, covered with snow of nuclear winter. It's music of dark overcastted sky, and huge rusty broken cars, living alone in their own eternal cycle. They assemble creatures from odd details and disassemble to assemble again.

With AMPOS Massimo Magrini set a standard in deeply emotional dark ambient noise and many of his following releases went in that vein of evocative intensity and monolithic sound. In addition to the remastered eleven tracks of the original version this issue includes two bonustracks recorded with the same set-up from that closes the circle of this timeless masterpiece.

This is the original first edition in a heavy brass box treated with acid. Four album tracks correspond with four seasons, four states of the soul Summer - repetitive loops become overgrown with the juicy flesh of atonal sound and transform into sampled rhythms flown over by a soft guitar tune.

Autumn - the rhythm is reduced to a hardly evident monotonous shroud, the atmosphere becomes more melodic and melancholic and in the end turns into a heart-piercing guitar solo. Winter - time for sleep and detachment: icy ringing, the slow breath of bass impulses, the rustling of electronics and sluggish drones painting vast snowy soundscapes.

And finally spring - the drone ambient nature unfolds large as life, majestic sonic waves sweep accompanied by a swarm of tiny sounds awoken to life again The first two tracks were recorded in and released on CD-R by the Italian label Blade Records in in a very limited edition , two others were recorded in and thus completed the natural cycle of this album.

We present the fundamental work by the French musical formation completely dedicated to the mysterious personality of Baron Rudolf von Sebottendorf and his work "Der Talisman des Rosenkreuzers" published in in Germany.

One of the founders of powerful secret organisation "Thule Society", a member of Turkish masonic lodge "Order of Rose Wreath", a numerologist, an occultist, a Sufi practicioner with misty entangled fate - he fits very well for a subject of detailed study, and one of the forms of it is this album.

Musically, you'll hear one of the most powerful combinations of martial, neoclassic and ambient. From the very first seconds it goes deep in the significant years of the XX century, grandiose flashes - slices of troublous times, exotic geographic locations, dangerous people, occult-war intrigues and famous mystical German movement.

Walls of heavy drones, explosive drumming and songs of dervishes, sublime samples of classics and dark rhythms encoded by electronics, a whisper from the other world, making heart beat high. During all the long and comprehensive material there is an intuitive investigation of entangled weltanschauung of "the baron", a combination of sufism, masonry and aryosophy. We present this long awaited split album of awesome quality. One of the best releases of UFA Muzak corporation, hard and important for understanding and inner interpretation.

The long monumental material of this otherworldly dedication to the most significant figure of mystical aryan movement consists of equal parts - contributions made to the full extent and dignity by French military ambient and Argentinian guitar drone noise.

This album is like an initiation, to pass it through, listen and submerge in it, one has to have a strong will and true belief in immortality of human soul. Through noise, slavery and pain of this world belonging to the Tsar who captured souls in senseless and eternal circle, appear exceedingly delicate gleams of light, coming through into the continual space, these flamy messages of runic forms, true symbols against death and entropy.

They exist, come through the chosen ones and represent the last hope. The voice of gnostic prophet Miguel Serrano is heard in sparse spheres, his speech is eternal, once said, wherever he is now.

From the stars, it's breezing real all-penetrating cold Petersburg-based saxophonist Igor V. Definitely one of Bardoseneticcube's most singular and musical works, with a mixture of irradiated electronics, hazy lunar jazz, sedated drones and urban soundscapes. Artwork by STPo. The music weaves dark electronics and industrial dub with heavy atmosphere. Bunker - totalitarian Power Electronics with genocidal video from 3rd Reich archive.

Pugna - shamanistic Drone Industrial plus ritual animation. Limited to copies. You're dead. This collection takes us further back in time to a more raw and singular vision, whilst still infused with passionate vocals and eerie religious allusions that would eventually lead to a development of increasingly more compositional elements in the Burial Hex cycle. Without as much focus on otherworldly hybrids, yet still organically eclectic, this offering will bring the grinding grey atmospherics and the nauseating aggression of early Horror Electronics into focus.

Artwork by Nathaniel Ritter Kinit Her. He adore music from his early childhood. He began from hip-hop and came to electronic music. His concert program started with idm project CAST when he was In Denis came to Moscow, where his first album released.

A hypnotic, slowly-evolving drone with waves of mysterious sounds, static and glitches. The second piece, on the other hand, finds Ralf Wehowsky composing a frenzied journey into otherworldly realms using sound material from Andrew Chalk and Eric Lanzillotta Eye Music.

These pieces reflect a sound unique from the work of any of the three individual participants, but clearly related. Subtle, but full of detail for the willing listener. Cover painting by Andrew Chalk. Remastered for CD from the original master recordings. Under the name of Cisfinitum, he has taken a syncretic approach to an often codified genre, uniting his formal training as a violinist at the Moscow State University with his affinity for concrete sounds and experimental structures.

Past releases have shown a capacity to synthesize these factors at times while emphasizing the contrasts between them at others, sometimes over the course of a single track.

In this aspect, this album follows the tradition faithfully Tactio is the live recording of a Cisfinitum concert at the St. Petri Dom St. Peter's Cathedral in Bremen, on November 24, The particular and as expected highly favorable acoustics of this environment were consistently used not only as an enhancing effect but as an integral foundation for the performance, making it unmistakably tied to its context. Presented in the form of six continuous tracks, the album is a contemplative composition of vibrant drones, reverberating bells and synthesized resonance, gracefully evolving from the celestial tones of its start to the tellurian pulses of its climax.

This is a piece of work that is elaborate in its simplicity, and it's with much appreciation that it is presented here today. The beautiful iconic artwork by Evgeny Kuprienko further emphasizes the relic-like qualities of this recording.

Can perhaps be seen as Combative Alignments benchmark, offering 6 tracks that work as a virtual musical thoroughfare to a more dreamlike, illusory state. Deeply brooding atmospheres, where omniscient layers of drones and reverberating sound currents meet measured, ritual percussion as performed under the glowing, gloomy haze of a primordial sunrise.

And Outside Glows the Red Dawn shines a dim light on a world of obscure origin, full of dark Germanic mysticism and unearthly sonic terrain. On a whole, this is a more focused, deeper, and fluid recording than you've heard before, yet triumphantly carrying on the tradition laid down by previous releases.

The sound material on "Voltage Controlled Amplifier" originates from 4ch MTR cassette, 4 tracks, minutes, over 3 previously unreleased tracks. From ambient music to metal percussion and a whirlpool of noise.

Comes in a gatefold digisleeve. Roots dub, experimental electronic dub, ambient-dub - you find all major dub trends there. Ulitka Zen is an outstanding work of sound engineer and live-sessions master. Anyone who heard this release knows that the Babylon is going to fall.

Despite the new name, his musical stylistics is in the old vein - mega-old-school ritual ambient with hollow sound.

Monotonous subdued rhythms, low-frequency drone and looped fragments of string passages. One min. Package - folded sheet of golden paper with minimum of information. From beneath the roots bound by blizzard, behind the ancient bark, in the stone heart of the forest comes this music - metaphysical incarnation of the spirit of winter Frost and Hunger.

A borderline between autumnal and winter cycles, the only attempt to hide in wolf grass and survive in Snowstorm. A call of blood from the far North. Second full-length of Esche released by common will of the labels Valgriind e Alarmstufe prod. Ezhi and Petruccho?

No additional life has been gained but, looking at raw statistics, screening will appear to increase survival time: this gain is called lead time. Selection bias can arise from the fact that not everyone necessarily will participate in a screening program. There can be factors that differ between those willing to get tested and those 18 Screening for Colorectal Cancer KCE reports vol.

If people with a higher risk of a disease are more eager to be screened, for instance women with a family history of breast cancer joining a mammography program, then a screening test could cause the disease related mortality to look worse than in non-participants. This is because more people with the disease will participate, resulting in a higher incidence, in the screened population, of people dying from it.

Selection bias may also make a test look better than it really is. If a test is more available to young and healthy people for instance if people have to travel a long distance to get checked then less people in the target population would be detected with disease, and the test will seem to make a positive difference. Volunteer bias is a special kind of selection bias, created by the fact that screening invitations tend to be more readily accepted by health-conscious individuals who are likely to have a better outcome for reasons other than early detection of the disease.

In other words, individuals with a strong interest in health issues are more likely to participate, whereas the risk of these individuals may be lower, due to a more healthy lifestyle. Overdiagnosis bias: screening may identify abnormalities that would never cause a problem in a person's lifetime. An example of this is prostate cancer screening8, It has been said that "more men die with prostate cancer than from it".

Autopsy studies have shown that a high proportion of men who have died in other ways, have prostate cancer when the prostate is examined under a microscope. Aside from issues arising from unnecessary treatment prostate cancer treatment is by no means without risk , overdiagnosis makes a study look good at picking up abnormalities, even though they are sometimes harmless. Observation bias or observer bias is error introduced into measurement when observers overemphasize what they expect to find and fail to notice what they do not expect.

This is why medical trials are normally double-blind rather than single-blind. The overall effect of these biases tends to exaggerate the beneficial effect of screening.

To prove that screening is producing a real benefit, it is essential to carry out population-based randomized controlled trials in which the group randomized to screening is analyzed as a whole and includes those who refuse the invitation to be screened and those who develop cancers that are not detected by screening intention-to-screen principle.

Only if the disease-specific mortality in the whole of this group is significantly lower than in the randomly selected group, that is not offered screening, can we be sure that the screening process is producing a truly beneficial effect on disease outcome. The validity of this end point, however, rests on the assumption that cause of death can be determined accurately. An alternative end point is all-cause mortality, which depends only on the accurate ascertainment of deaths Major inconsistencies were identified in disease-specific and all-cause mortality endpoints in randomized cancer screening trials Because all-cause mortality is KCE reports vol.

The use of surrogate outcome measures in screening trials always bears a risk of biasing conclusions. So, the real question to be answered before spending considerable public health resources on the implementation of a mass screening program, is whether one should consider overall mortality and quality of survival19 as the only hard outcome measure of interest, especially in case of unsatisfactory screening uptake.

Like any medical test, the tests used in screening are not perfect. The test may miss people who have the disease false negative or may appear positive for those without disease false positive. Besides misdiagnosis and overdiagnosis, other potential adverse effects of screening are: 1. Stress and anxiety caused by a false positive screening result Unnecessary further investigation and treatment of false positive results.

Prolonging knowledge of an illness if nothing can be done about it. A false sense of security caused by false negative results, which may even delay final diagnosis. Unnecessary and uncomfortable procedures looking for a disease that is unlikely. Rectal bleeding was the most common symptom, followed by recent change in bowel habits, abdominal pain, tenesmus, rectal pain besides unexplained weight loss or anaemia. This undoubtly raises the question whether the FOBT was being ordered appropriately, but this issue will be dealt with in the chapter on clinical effectiveness and potential harms of CRC screening.

Screening is the examination of asymptomatic individuals in order to classify them as unlikely or likely to have a disease. A national screening program is an example of a population preventive strategy, where everyone in a particular age-group is invited to participate. Such strategy has the potential to identify a high proportion of individuals with early disease in a given population. This proportion depends on the uptake of screening and the sensitivity of the test chosen.

Even in cancer screening programs where uptake is high and the screening test is very sensitive, the vast majority of individuals who take part will not have cancer, so that the potential benefits of screening are available to a relatively small group. Surveillance, as opposed to screening, refers to monitoring individuals known to have a disease or to be at increased risk for a disease. For this population the potential benefit of surveillance is higher than that of screening in the population at large, because the prevalence of the disease is higher in this population.

Thus, the benefit-to-risk ratio of surveillance is more favourable than the benefit-to-risk ratio of screening. Therefore, for example, individuals who believe themselves to be at increased risk of developing colorectal cancer CRC may be more willing to accept the risks associated with surveillance. In this definition screening can either refer to a population based screening program average risk screening, population or mass screening , or to targeted screening for individuals with established risk factors or personal concerns about it also called sensitive screening.

Both methods imply different objectives and thus different requirements: if the aim is to reduce the burden of disease on a community the approach needed is population screening; this requires the use of a test associated with a high uptake and low cost. Implementation of CRC mass screening programs is indeed tedious, expensive and requires several barriers to be overcome.

It might therefore seem logical in some countries to concentrate public health resources on a selected sub-population, in which screening appears to be most meaningful and probably more cost-effective. Returning to definitions, we have to recognize that the demarcation line between surveillance and targeted screening remains fuzzy: should we consider a proven genetic predisposition as a pre-clinical phase of the disease and thus needing surveillance follow-up? And what should be done for patients with a KCE reports vol.

Should we label them for targeted screening or for surveillance? However, from the clinical point of view, such questions remain chiefly academic.

Based on the above considerations we framed a general classification scheme for CRC screening and surveillance Table 1. It can also make a study look well performing at picking up abnormalities, even though they might be harmless. For mass screening programs to be successful, utmost care should be devoted to a proper organisation and a suitable test in order to maximise participation rates and minimise potential harms.

In Belgium these ICD codes are used for recording causes of death. In clinical record registries such as the minimal data sets, however, the ICD-9CM33 coding system is still being used.

Here, colorectal cancers are covered by codes Topographical location and morphological histology features of neoplastic lesions are registered by means of the International Classification of Diseases for Oncology ICD-O coding system, currently in its third revision This is widely used by cancer registries and in anatomopathological protocols of resection specimens.

Worldwide, colorectal cancer is diagnosed every year in around 1 Million men and women, and about The most common incident form of cancer on the European Continent in was lung cancer Lung cancer was also the largest cause of cancer death Increase is more slowly in women and, at every age, women have a lower incidence of colorectal cancer than men More recent data from Flanders show slightly higher incidence numbers in the years - , a total of 8.

In Flanders colorectal cancer is the third most common cancer in men after prostate and lung cancer while it is the second most common cancer in women, only after breast cancer Figure 1. Figure 1: Most frequent cancers in Flanders source: Vlaams Agentschap Zorg en Gezondheid39 Figure 2 presents crude numbers of colorectal cancers by gender and age group in Flanders for the period - In absolute numbers, most colorectal cancers occur around the age of 70 - 74 in men and around the age of 75 - 79 in women.

Table 3: Estimated colorectal cases in Belgium Males 4. Expanding those age limits from 50 to 75 would correspond to more than half of the CRC cases in Belgium. Age-specific incidence rate is the number of new cases per year in a specific 5year age group per Age-specific incidence rates by gender for colorectal cancer in Flanders, years - , are presented in Figure 3.

Incidence data were calculated on the basis of the annual absolute incidence and age-specific population data from the National Institute of Statistics NIS. Distribution by localisation in Flanders - is shown in Figure 4. In short, it is the international language of colorectal cancer staging in all disciplines. The TNM system has three additional advantages over other staging systems. First, it is data-driven and has a process in place for continuous improvement based on ongoing expert review of existing data.

Second, it has a comprehensive set of definitions and rules of application that ensure uniform use. Third, it is multidisciplinary in design and is pertinent to all modern techniques of stage evaluation. Figure 5 shows the distribution of colorectal cancer TNM stages in males and females in Flanders for the years - Stage distributions in males and females show a very comparable pattern.

These data also show that the stage distribution is very similar in the different age categories not shown. This staging illustrates the extent of colorectal cancer at the time of diagnosis and enabled the classification of patients into prognostically comparable categories.

Although the importance of good staging is well-recognised, these data were not always passed on to the cancer registry. In addition, these data may have been incomplete or missing from the medical files. These are possible reasons why the cancer registry encountered an important percentage of missing data. With the introduction in of financial reimbursement for multidisciplinary oncological consultations, it might be expected that these data will be more complete in the future because payment is only made if these data are completed.

It does not take into account the level of nodal involvement or the grade of the tumor. It is, however, still widely used in surgical publications in Belgium and other European countries.

After standardising for age, there are yearly about 12 colorectal cancer deaths per This mortality rate remained rather constant throughout those years. Apparently there are wide variations in diagnostic and surgical practice between Europe and the USA.

Although in absolute numbers more elderly women died from colorectal cancer Figure 8 , the age-specific mortality rate was higher in men, due to the demographic reality that there are more elderly women left at those ages.

Relative survival is a frequently used parameter in cancer epidemiology and forms a good approach to diseasespecific survival.

The relative survival rates reflect an estimate of the expected survival of cancer patients, in which causes of death other than cancer have been left aside. Relative 5-year survival is calculated by dividing the observed survival by the expected survival in a group of people with the same gender and age structure from the general population.

Stage at diagnosis TNM staging, 5th edition is a strong predictor of survival43, 41, as illustrated by Figure 9 and Figure 10 showing the observed and relative survival curves respectively of patients with CRC by stage. The SEER program is a population-based tumor registry that collects patient records from multiple sites across the United States. These data essentially show a similar importance of stage at diagnosis as observed in Flanders. Limiting screening or early cancer detection to only these persons at increased risk would obviously miss the majority of colorectal cancers.

Specific genetic mutations have been identified as the cause of inherited cancer risk in some CRC-prone families. It is likely that other yet undiscovered major genes and background genetic factors contribute to the development of colorectal cancer. Moderate familial clustering, on the other hand, represents a heterogeneous group attributable to a combination of genes, environment, and chance. This chapter does not deal with personal lifestyle, dietary nor environmental risk factors.

This risk increases with sizes greater than 1 cm for any adenomatous polyp, the number of polyps, and villous or tubulovillous histology Efforts to identify causes of CRC and to develop effective preventive measures have led to the hypothesis that adenomatous polyps adenomas are precursors for the vast majority of colorectal cancers. Evidence supporting the adenomacarcinoma sequence in colorectal cancer is summarized in Table Adenomas and carcinomas are frequently contiguous 2.

The anatomical distribution of adenomas and carcinomas is similar 3. Familial adenomatous polyposis FAP is unequivocally premalignant Adenomas and carcinomas share similar patterns of chromosomal abnormality and 7. All publicatons59, 60, 66, 67, 61, 62 concur on: 1. The precise timing within this interval should be based on other clinical factors such as prior colonoscopy findings, family history, and the preferences of the patient and judgment of the physician.

Patients with sessile adenomas67 that are removed piecemeal should be considered for follow up at short intervals 2 to 6 months to verify complete removal. Completeness of removal should be based on both endoscopic and pathologic assessments. Patients with small rectal hyperplastic polyps should be considered to be at average risk, and therefore the interval before the subsequent colonoscopy should be 10 years. An exception is patients with a hyperplastic polyposis syndrome They are at increased risk for adenomas and colorectal cancer and need to be identified for more intensive follow up.

Risk is highest for women with the primary diagnosis prior to age 50 years However, this observation is based on data that did not exclude patients with Hereditary Nonpolyposis Colorectal Cancer HNPCC who may account for some of the observed risk One cross-sectional study82 examined the relationship between distal diverticulosis and risk for colorectal neoplasia in patients undergoing firsttime colonoscopy for any indication.

Patients with prior polypectomy, colonic resection, or inflammatory bowel disease were excluded. Patients completed a survey about risk factors for CRC prior to colonoscopy. Endoscopists, blinded to study objective and survey results, recorded the size, extent none, few, or many , and location of diverticuli and polyps. Hence, distal diverticulosis appears not to be independently associated with proximal neoplasia in men or women.

The earliest recorded is 10 years after ureterosigmoidostomy The observation that the mean latent period for the development of adenomas is 19,8 years and for carcinomas is 25,8 years suggests that the adenoma-carcinoma sequence takes a mean of six years It is uncertain whether the neoplasms arise from the intestinal or the ureteric epithelium or from the anastomosis itself. This risk is greater when associated with early age of onset or multiple affected relatives Furthermore, there is increasing awareness among relatives of patients with colorectal cancer that they may be at increased risk for this disease and consequently there is rising demand for targeted screening29, Family history risk factors for CRC include: 1.

Two FDR diagnosed at any age. A single FDR diagnosed after age 60 may put patients at a very slightly increased risk. The U. Multisociety Task Force on Colorectal Cancer recommends starting routine screening at age 40 for patients with a family history of colorectal cancer in a single FDR diagnosed over the age of , Individuals who have FDR with adenomatous polyps may be at increased risk for the development of colorectal cancer, When two family members have adenomatous polyps, regardless of the age of diagnosis, targeted screening is appropriate.

As the age of diagnosis in the FDR decreases, the risk to the individual compared to the average population increases. Relevant hereditary conditions include, , , 1. Additional syndromes continue to be defined as new genes are linked to the development of colonic polyps and cancer, , The two cohorts were followed for the development of colorectal cancer over 6, respectively 8 years. The results are presented in Table 6. This yielded 35 publications dealing with familial aggregation estimated from family studies based on an index person and, on abstract review, we retained 16 of them for further evaluation.

The remaining 19 articles were discarded as they either studied specific genetic polymorphisms, had too small a study population, were simple review articles or chiefly treated non-related issues: pharmacological, surgical issues, etc. Indeed, there are very few high-risk persons in the population as a whole. Population trials on cancer prone persons are feasible, but vast numbers have to be pre-screened to identify the few people with a high hereditary risk and willing to accept screening within a controlled trial.

In the results of a randomized trial conducted in France were published The trial was based on colonoscopic screening for colorectal cancer on a subgroup of high-risk group persons determined by familial history analysis. Among the 77 members of the French Institutional Preventive Center Network, 37 took part in this protocol. During the first 3 years, The enrollment process was particularly time-consuming, since a large amount of information had to be delivered to the participants.

The low rates of recruitment were mainly due to the intercenter heterogeneity KCE reports vol. Others studies are population-based prospective cohort studies or retrospective population studies, , To determine to what extent individuals with various family histories of colorectal cancer are at risk a prospective, observational study of high risk families, followed up over 16 years, was carried out in a tertiary referral family cancer clinic in London Colonoscopy was initially offered at five year intervals or three year intervals if an adenoma was detected.

The incidence of adenomas with high risk pathological features or cancer was analysed by age, the extent of the family history, and findings on previous colonoscopies. The cohort was flagged for cancer and death.

The study showed clearly that colonoscopic surveillance reduces the risk of colorectal cancer in people with a strong family history; members of families with HNPCC require surveillance with short intervals.


Seem It ,ache do 1. Ft Ia cettaa qite t. Oclitenta articulosfas ,, E. The iFOBT was also accompanied with a questionnaire on colorectal cancer risk factors, making it difficult to interpret the results. Fu6s do baberlu ,, deJ. Pit ft ar. Dsena I ,Pdn C. I -Una "'.
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